Nurse Practitioner Pay

Durham vs Sanford: Nurse Practitioner Salary (2026)

Compare nurse practitioner salaries between Durham, NC and Sanford, NC. All figures are 2026 estimates projected from BLS 2025 data.

Durham, NC
$136,864
$65.80/hr
Sanford, NC
$130,320
$62.65/hr

Side-by-Side Comparison

MetricDurham, NCSanford, NC
Median Salary$136,864$130,320
Hourly Rate$65.80$62.65
Entry Level (P10)$111,933$101,011
25th Percentile$128,247$116,020
75th Percentile$152,237$152,287
Top Earner (P90)$172,824$166,160
Total Employed1,4505
Side-by-side bar chart comparing Durham ($136,864) and Sanford ($130,320) nurse practitioner salaries.DurhamSanfordMedian Salary$136,864$130,320Entry Level (P10)$111,933$101,011Top Earner (P90)$172,824$166,160US Median $136,864

Verdict

Durham, NC offers better overall compensation for nurse practitioners, winning 4 out of 4 metrics compared to Sanford.

The salary gap between Durham and Sanford is $6,544 (5.02%). Durham's median is +0.00% compared to the US national median of $136,864.

Salary Range Comparison

The full salary range (10th to 90th percentile) in Durham spans $60,891,Sanford spans $65,149. Sanford has a wider pay range, suggesting more variation in pay between entry-level and experienced nurse practitioners.

Durham
P10 (Entry)$111,933
P25$128,247
Median$136,864
P75$152,237
P90 (Top)$172,824
Sanford
P10 (Entry)$101,011
P25$116,020
Median$130,320
P75$152,287
P90 (Top)$166,160

Cost-of-Living Adjusted Comparison

After cost-of-living adjustment, Durham ($140,270 effective) pays 0.75% more than Sanford ($139,231 effective).

Durham
Nominal: $136,864
CoL Index: 97.572
Adjusted: $140,270
Sanford
Nominal: $130,320
CoL Index: 93.6
Adjusted: $139,231

Cost-of-living adjustment: salary × (100 / CoL index). Index of 100 = national average.

Which City Is Right for You?

Choose Durham if…

  • Higher median salary ($136,864/year)
  • Better top-earner potential ($172,824)
  • Larger job market (1,450 employed)
  • Better purchasing power (CoL-adjusted: $140,270)
  • You prefer the North Carolina area and lifestyle

Choose Sanford if…

  • You prefer the North Carolina area and lifestyle

Historical Salary Growth Comparison

Based on BLS OEWS metropolitan area data, nurse practitioner salaries in Durham grew 25.0% from 2019 to 2025, compared to 11.9% growth in Sanford over the same period.

Durham, NC

+25.0%

$105,830 (2019) → $132,300 (2025)

Sanford, NC

+11.9%

$112,587 (2024) → $125,974 (2025)

View Full Salary Data

Frequently Asked Questions

Which city pays nurse practitioners more: Durham or Sanford?

Durham has a higher median nurse practitioner salary at $136,864/year, compared to Sanford at $130,320/year — a difference of $6,544 (5.02%).

What is the hourly rate difference between Durham and Sanford?

Durham nurse practitioners earn $65.80/hr while Sanford hygienists earn $62.65/hr (2026 est.).

Should I relocate from Durham to Sanford as a nurse practitioner?

Consider more than just salary when comparing Durham and Sanford. Factor in cost of living (CoL-adjusted: Durham = $140,270, Sanford = $139,231), job availability (1,450 vs 5 employed), commute, and career growth potential.

What do entry-level nurse practitioners earn in Durham vs Sanford?

Entry-level (10th percentile) nurse practitioners earn $111,933 in Durham and $101,011 in Sanford. The Durham area offers higher starting salaries.

Related Comparisons

MG

Written by Maria Gonzalez, MSN, NP-C

Career Analyst

Maria has 10 years of experience in adult healthcare. She works in a community health clinic. Her specialty is chronic disease management.

Clinically reviewed by James Patel, DNP, APRNData verified by Aisha Khan, MSN, FNP-BC

Methodology & Data Source

All salary figures are 2026 projections based on BLS OEWS May 2025 data. A 3.45% CAGR (derived from 6-year national BLS trends) was applied to estimate current compensation. Cost-of-living adjustments use BEA Regional Price Parity data. Actual salaries vary by employer, certifications, and experience.

Data Sources & Methodology

Source: BLS, OEWS , released .

Compiled and verified by Maria Gonzalez, MSN, NP-C, a licensed nurse practitioner with 10+ years of clinical experience. · View source data at BLS.gov