Nurse Practitioner Pay

San Francisco vs Thousand Oaks: Nurse Practitioner Salary (2026)

Compare nurse practitioner salaries between San Francisco, CA and Thousand Oaks, CA. All figures are 2026 estimates projected from BLS 2025 data.

San Francisco, CA
$226,638
$108.96/hr
Thousand Oaks, CA
$153,312
$73.71/hr

Side-by-Side Comparison

MetricSan Francisco, CAThousand Oaks, CA
Median Salary$226,638$153,312
Hourly Rate$108.96$73.71
Entry Level (P10)$158,568$120,721
25th Percentile$182,579$138,479
75th Percentile$250,256$185,810
Top Earner (P90)$283,412$209,079
Total Employed3,11032
Side-by-side bar chart comparing San Francisco ($226,638) and Thousand Oaks ($153,312) nurse practitioner salaries.San FranciscoThousand OaksMedian Salary$226,638$153,312Entry Level (P10)$158,568$120,721Top Earner (P90)$283,412$209,079US Median $136,864

Verdict

San Francisco, CA offers better overall compensation for nurse practitioners, winning 4 out of 4 metrics compared to Thousand Oaks.

The salary gap between San Francisco and Thousand Oaks is $73,326 (47.83%). San Francisco's median is +65.59% compared to the US national median of $136,864.

Salary Range Comparison

The full salary range (10th to 90th percentile) in San Francisco spans $124,844,Thousand Oaks spans $88,358. San Francisco has a wider pay range, meaning more potential for high earners but also more variation.

San Francisco
P10 (Entry)$158,568
P25$182,579
Median$226,638
P75$250,256
P90 (Top)$283,412
Thousand Oaks
P10 (Entry)$120,721
P25$138,479
Median$153,312
P75$185,810
P90 (Top)$209,079

Cost-of-Living Adjusted Comparison

After cost-of-living adjustment, San Francisco ($196,032 effective) pays 44.61% more than Thousand Oaks ($135,554 effective).

San Francisco
Nominal: $226,638
CoL Index: 115.613
Adjusted: $196,032
Thousand Oaks
Nominal: $153,312
CoL Index: 113.1
Adjusted: $135,554

Cost-of-living adjustment: salary × (100 / CoL index). Index of 100 = national average.

Which City Is Right for You?

Choose San Francisco if…

  • Higher median salary ($226,638/year)
  • Better top-earner potential ($283,412)
  • Larger job market (3,110 employed)
  • Better purchasing power (CoL-adjusted: $196,032)
  • You prefer the California area and lifestyle

Choose Thousand Oaks if…

  • You prefer the California area and lifestyle

Historical Salary Growth Comparison

Based on BLS OEWS metropolitan area data, nurse practitioner salaries in San Francisco grew 58.6% from 2019 to 2025, compared to -20.6% growth in Thousand Oaks over the same period.

San Francisco, CA

+58.6%

$138,100 (2019) → $219,080 (2025)

Thousand Oaks, CA

+-20.6%

$186,582 (2024) → $148,199 (2025)

View Full Salary Data

Frequently Asked Questions

Which city pays nurse practitioners more: San Francisco or Thousand Oaks?

San Francisco has a higher median nurse practitioner salary at $226,638/year, compared to Thousand Oaks at $153,312/year — a difference of $73,326 (47.83%).

What is the hourly rate difference between San Francisco and Thousand Oaks?

San Francisco nurse practitioners earn $108.96/hr while Thousand Oaks hygienists earn $73.71/hr (2026 est.).

Should I relocate from San Francisco to Thousand Oaks as a nurse practitioner?

Consider more than just salary when comparing San Francisco and Thousand Oaks. Factor in cost of living (CoL-adjusted: San Francisco = $196,032, Thousand Oaks = $135,554), job availability (3,110 vs 32 employed), commute, and career growth potential.

What do entry-level nurse practitioners earn in San Francisco vs Thousand Oaks?

Entry-level (10th percentile) nurse practitioners earn $158,568 in San Francisco and $120,721 in Thousand Oaks. The San Francisco area offers higher starting salaries.

Related Comparisons

MG

Written by Maria Gonzalez, MSN, NP-C

Career Analyst

Maria has 10 years of experience in adult healthcare. She works in a community health clinic. Her specialty is chronic disease management.

Clinically reviewed by James Patel, DNP, APRNData verified by Aisha Khan, MSN, FNP-BC

Methodology & Data Source

All salary figures are 2026 projections based on BLS OEWS May 2025 data. A 3.45% CAGR (derived from 6-year national BLS trends) was applied to estimate current compensation. Cost-of-living adjustments use BEA Regional Price Parity data. Actual salaries vary by employer, certifications, and experience.

Data Sources & Methodology

Source: BLS, OEWS , released .

Compiled and verified by Maria Gonzalez, MSN, NP-C, a licensed nurse practitioner with 10+ years of clinical experience. · View source data at BLS.gov