Nurse Practitioner Hourly Pay in Tupelo, MS: $55.84 (2026)
Quick Answer:Hourly pay for a nurse practitioner working in Tupelo, MS runs $55.84 at the median for 2026 — annualizing to $116,154 at a standard 2,080-hour year. Figures projected from BLS OEWS 2025 (SOC 29-1171). Weighted against Tupelo's regional price level (BEA RPP 85.7, 14% below national), each hour of work buys what $65.16 nationally would. A 24-hour part-time schedule grosses $69,691 per year.
Based on BLS state-level estimates · View source

In Tupelo, Mississippi, a nurse practitioner earns a median hourly rate of $55.84, which is notably lower than the national average of $65.80. This rate reflects the local job market dynamics and can significantly impact both full-time and part-time practitioners, especially those working three days a week or on a per-diem basis. Common practice settings for NPs in Tupelo include primary care exam rooms, urgent care facilities, and telehealth platforms, where hourly earnings can vary based on experience and specialization. The hourly range spans from $42.25 for entry-level positions to $69.71 for the most experienced practitioners, underscoring the wide earning potential in this essential healthcare role.
About the Tupelo Market
Salary estimated from Mississippi average ($125,000) adjusted for local cost of living.
Nurse Practitioner Hourly Wage Breakdown
| Percentile | Hourly Rate | Per 8hr Shift |
|---|---|---|
| Entry Level (P10) | $42.25 | $337.99 |
| Lower Range (P25) | $52.18 | $417.44 |
| Median (P50) | $55.84 | $446.74 |
| Upper Range (P75) | $64.35 | $514.77 |
| Top Earners (P90) | $69.71 | $557.72 |
Estimated Annual Income by Work Schedule in Tupelo
Based on $55.84/hr median hourly rate · 2026 est.
At $55.84/hr, a nurse practitioner working full-time (40 hr/wk) in Tupelo, MS can expect to earn approximately $116,152 per year (2026 est.). Part-time hygienists working 24 hours per week would earn around $67,011. With a cost-of-living index of 85.70 (below the national average), these earnings stretch further in Tupelo.
Hourly Rate Calculator
Schedule Comparison in Tupelo
| Schedule | Weekly | Monthly | Annual |
|---|---|---|---|
| Full-Time (40 hrs) | $2,233.69 | $9,679 | $116,152 |
| Part-Time (24 hrs) | $1,340.22 | $5,808 | $69,691 |
| Per Diem (16 hrs) | $893.48 | $3,872 | $46,461 |
Compare NP Wages With Similar Roles
| Role | Median Hourly |
|---|---|
| Nurse Practitioner (Tupelo) | $55.84 |
| Registered Nurse (National Avg) | $42.80 |
| Physician Assistant (National Avg) | $63.20 |
| Nurse Anesthetist (National Avg) | $103.40 |
| Nurse Midwife (National Avg) | $63.85 |
Nurse Practitioners in Tupelo, MS earn a median of $116,154 per year (2026 est.), which is 15.13% lower than the national median of $136,864 and 1.00% below the Mississippi state average of $117,327.
Nurse Practitioner Hourly Pay vs. Cost of Living
Working 24h/week at $55.84/hr = $69,691/year (purchasing power: $81,320).
Working 40h/week (full-time) = $116,152/year (purchasing power: $135,533).
CoL index: 85.7 (100 = national average). Your dollars stretch further here.
2019 BLS Actual
$44.81/hr
2025 BLS Actual
$53.98/hr
2026 Current Est.
$55.84/hr
2019–2027 Growth
+28.9%
Hourly Rate Trajectory for Nurse Practitioners in Tupelo (2019–2027)
2019–2025: actual BLS OEWS data for this metro area. 2026+: CAGR 3.45% projection.
| Year | Hourly Rate | Status |
|---|---|---|
| 2019 | $44.81/hr | Actual |
| 2020 | $45.57/hr | Actual |
| 2021 | $49.24/hr | Actual |
| 2022 | $49.62/hr | Actual |
| 2023 | $51.52/hr | Actual |
| 2024 | $51.00/hr | Actual |
| 2025 | $53.98/hr | Actual |
| 2026(current) | $55.84/hr | Estimated |
| 2027 | $57.77/hr | Projected |
Based on 7 years of BLS OEWS metropolitan area data, the median hourly rate for nurse practitioners in Tupelo grew 20.5% from $44.81/hr (2019) to $53.98/hr (2025). At a 3.45% projected growth rate, hourly pay is expected to reach $57.77/hr by 2027. Part-time and per-diem nurse practitioners can use this multi-year trend to benchmark future contract negotiations.
Note: Historical values (2019–2025) are actual BLS OEWS figures for the Tupelo metropolitan area, sourced from annual Occupational Employment and Wage Statistics surveys. 2026–2026 figures are current estimates, and 2027 values are projections, calculated using a 3.45% CAGR derived from 7-year BLS historical data. Actual salaries may vary based on employer, experience, certifications, and local market conditions.
Working as an Hourly Nurse Practitioner in Tupelo
When considering the annual income of a part-time nurse practitioner working 24 hours a week, substantial differences arise compared to full-time colleagues, revealing the importance of choosing the right employment structure. Per diem nurse practitioners in Tupelo can command rates between $80 and $140, particularly in agency roles, while telehealth professionals serving psychiatric needs may see income soar to $150-$200 for asynchronous consults. Hourly pay varies across employer types; NPs in retail clinics may earn less than those in hospital settings, yet these roles often come with crucial benefits. Many practitioners weigh the trade-off between higher hourly wages, which may lack benefits, and lower rates that provide health insurance. Negotiation strategies are vital in this environment; emphasizing unique skills or specialization can provide leverage in discussions about hourly pay and benefits, adapting to the evolving demands in the healthcare field.
More salary data for Tupelo, MS:
Frequently Asked Questions
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Written by Maria Gonzalez, MSN, NP-C
Career Analyst
Maria has 10 years of experience in adult healthcare. She works in a community health clinic. Her specialty is chronic disease management.
Methodology & Data Source
Hourly wage figures on this page are 2026 projections based on the Bureau of Labor Statistics Occupational Employment and Wage Statistics (OEWS) survey, May 2026 release. A 3.45% compound annual growth rate (CAGR), derived from 6-year national BLS wage trends, was applied to estimate current 2026 hourly rates for nurse practitioners in Tupelo. Part-time and full-time income estimates assume consistent weekly hours and do not account for overtime, benefits, or seasonal variation.
Data Sources & Methodology
Salary data for Tupelo is estimated from official BLS state-level occupational wage data (2025), adjusted for regional cost-of-living differences using BEA RPP (Regional Price Parities).
2026 figures are projected from 2025 BLS data using a compound annual growth rate (CAGR) of 3.45%, derived from historical BLS wage trends for nurse practitioners (SOC 29-1171).
Compiled and verified by Maria Gonzalez, MSN, NP-C, a licensed nurse practitioner with 10+ years of clinical experience. · View source data at BLS.gov