Nurse Practitioner Salary in Columbus, MS: $110,295 (2026)
Quick Answer:A full-time nurse practitioner in Columbus, MS earns a median $110,295/year (≈ $53.03/hour) in nominal terms for 2026 — projected from BLS OEWS 2025 (SOC 29-1171). Once you factor in Columbus's price level (14% below national, BEA RPP 85.7), that paycheck buys what $128,699 would nationally. Nominal pay sits 6.0% below the Mississippi state average.
Based on BLS state-level estimates · View source

Nurse practitioners in Columbus, Mississippi, can expect a median salary of $110,295 in 2026, a figure that trails the national median of $136,864 by nearly 19.41%. The local salary range, spanning from $85,679 at the 10th percentile to $132,679 at the 90th percentile, reflects the varying demands and specializations within the nursing field. Particularly, psychiatric mental health nurse practitioners (PMHNPs) often command the highest salaries, given the growing mental health needs, followed by adult-gerontology acute care nurse practitioners (AGACNPs) and family nurse practitioners (FNPs). These estimates are derived from 2025 BLS data, projected for 2026, and account for regional economic conditions, which play a significant role in salary determinations within the city.
About the Columbus Market
Salary estimated from Mississippi average ($125,000) adjusted for local cost of living.
Salary Breakdown
| Percentile | Annual | Hourly |
|---|---|---|
| Entry Level (P10) | $85,679 | $41.19 |
| Lower Range (P25) | $104,378 | $50.18 |
| Median (P50)(typical) | $110,295 | $53.03 |
| Upper Range (P75) | $124,979 | $60.08 |
| Top Earners (P90) | $132,679 | $63.79 |
Median Salary Position
19.41% below the national average
2026 Salary Percentile Distribution in Columbus
In Columbus, MS, the nurse practitioner salary spread from the 10th to 90th percentile is $47,000 (2026 est.). At $110,295, the local median is 19.41% below the national median of $136,864.
Salary Calculator
At 40 hours/week in Columbus: You'd be above the median
How Columbus Nurse Practitioner Pay Compares
Columbus median: $110,295/year (2026)
| Compared To | Median Salary | Columbus Pays |
|---|---|---|
| Mississippi Average | $117,335 | -6.00% less |
| National Average | $136,864 | -19.41% less |
Nurse Practitioners in Columbus, MS earn a median of $110,295 per year (2026 est.), which is 19.41% lower than the national median of $136,864 and 6.00% below the Mississippi state average of $117,335.
Cost-of-Living Adjusted Salary
Columbus has a cost of living 14.30% below the national average, meaning your salary goes further here.
Adjusted salary = nominal × (100 / CoL index). CoL index: 100 = national average.
Columbus, MS has a cost-of-living index of 85.7 (below the national average of 100). A nurse practitioner earning $110,295 nominally has purchasing power equivalent to $128,699 in an average-cost city — an effective 16.69% boost.
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2019 BLS Actual
$88,501
2025 BLS Actual
$106,617
2026 Current Est.
$110,295
2019–2027 Growth
+28.9%
Salary Trajectory for Nurse Practitioners in Columbus (2019–2027)
2019–2025: actual BLS OEWS data for this metro area. 2026+: CAGR 3.45% projection.
| Year | Annual Salary | Status |
|---|---|---|
| 2019 | $88,501 | Actual |
| 2020 | $90,000 | Actual |
| 2021 | $97,253 | Actual |
| 2022 | $98,002 | Actual |
| 2023 | $101,750 | Actual |
| 2024 | $100,734 | Actual |
| 2025 | $106,617 | Actual |
| 2026(current) | $110,295 | Estimated |
| 2027 | $114,100 | Projected |
Based on 7 years of BLS OEWS data for the Columbus metropolitan area, the median nurse practitioner salary grew 20.5% from $88,501 (2019) to $106,617 (2025). At a 3.45% compound annual growth rate, salaries are projected to reach $114,100 by 2027 — a total increase of $25,599 (28.93%) from 2019.
Note: Historical values (2019–2025) are actual BLS OEWS figures for the Columbus metropolitan area, sourced from annual Occupational Employment and Wage Statistics surveys. 2026–2026 figures are current estimates, and 2027 values are projections, calculated using a 3.45% CAGR derived from 7-year BLS historical data. Actual salaries may vary based on employer, experience, certifications, and local market conditions.
Salary by Experience Level
| Experience | Estimated Salary Range |
|---|---|
| 0-2 years (New Graduate) | $85,679 – $104,378 |
| 3-5 years (Mid Career) | $104,378 – $110,295 |
| 5+ years (Experienced) | $110,295 – $124,979 |
| 10+ years (Top Earner) | $124,979 – $132,679 |
NP salary ranges estimated from BLS percentile data. Individual nurse practitioner compensation varies by employer, certifications, and specialization.
Nurse Practitioner Job Market in Columbus
With only six nurse practitioners currently employed in Columbus, the job market presents both challenges and opportunities. The cost of living index here sits at 85.7, indicating that while salaries may be lower than the national average, the lower living expenses can enhance purchasing power for practitioners. Among local employers, outpatient hospital clinics and specialty clinics tend to offer higher compensation compared to retail clinics or urgent care chains. The disparity in pay also arises from specialties, with PMHNPs benefiting from strong demand and potential productivity bonuses. For nurse practitioners aiming to maximize their pay in Columbus, exploring opportunities in settings that recognize full-practice authority or offer collaborative agreements could yield better financial outcomes. Engaging in telehealth platforms may also provide additional income streams, enhancing overall earning potential in this evolving healthcare landscape.
More salary data for Columbus, MS:
Frequently Asked Questions
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Written by Maria Gonzalez, MSN, NP-C
Career Analyst
Maria has 10 years of experience in adult healthcare. She works in a community health clinic. Her specialty is chronic disease management.
Methodology & Data Source
Salary figures on this page are 2026 projections based on the Bureau of Labor Statistics Occupational Employment and Wage Statistics (OEWS) survey, May 2026 release. The BLS reported a median annual salary of $106,617 for nurse practitionersin the Columbus metropolitan area. A 3.45% compound annual growth rate (CAGR), calculated from 6-year national BLS wage trends, was applied to project current 2026 compensation. Percentile ranges (P10–P90) represent the full salary distribution across experience levels and practice settings in this market.
Data Sources & Methodology
Salary data for Columbus is estimated from official BLS state-level occupational wage data (2025), adjusted for regional cost-of-living differences using BEA RPP (Regional Price Parities).
2026 figures are projected from 2025 BLS data using a compound annual growth rate (CAGR) of 3.45%, derived from historical BLS wage trends for nurse practitioners (SOC 29-1171).
Compiled and verified by Maria Gonzalez, MSN, NP-C, a licensed nurse practitioner with 10+ years of clinical experience. · View source data at BLS.gov