Nurse Practitioner Pay

Nixa vs St. Louis: Nurse Practitioner Salary (2026)

Compare nurse practitioner salaries between Nixa, MO and St. Louis, MO. All figures are 2026 estimates projected from BLS 2025 data.

Nixa, MO
$127,709
$61.40/hr
St. Louis, MO
$136,120
$65.44/hr

Side-by-Side Comparison

MetricNixa, MOSt. Louis, MO
Median Salary$127,709$136,120
Hourly Rate$61.40$65.44
Entry Level (P10)$103,363$112,078
25th Percentile$115,976$131,857
75th Percentile$147,361$159,830
Top Earner (P90)$158,525$169,948
Total Employed63,430
Side-by-side bar chart comparing Nixa ($127,709) and St. Louis ($136,120) nurse practitioner salaries.NixaSt. LouisMedian Salary$127,709$136,120Entry Level (P10)$103,363$112,078Top Earner (P90)$158,525$169,948US Median $136,864

Verdict

St. Louis, MO offers better overall compensation for nurse practitioners, winning 4 out of 4 metrics compared to Nixa.

The salary gap between Nixa and St. Louis is $8,411 (6.59%). St. Louis's median is -0.54% compared to the US national median of $136,864.

Salary Range Comparison

The full salary range (10th to 90th percentile) in Nixa spans $55,162,St. Louis spans $57,870. St. Louis has a wider pay range, suggesting more variation in pay between entry-level and experienced nurse practitioners.

Nixa
P10 (Entry)$103,363
P25$115,976
Median$127,709
P75$147,361
P90 (Top)$158,525
St. Louis
P10 (Entry)$112,078
P25$131,857
Median$136,120
P75$159,830
P90 (Top)$169,948

Cost-of-Living Adjusted Comparison

After cost-of-living adjustment, St. Louis ($143,152 effective) pays 0.43% more than Nixa ($142,532 effective).

Nixa
Nominal: $127,709
CoL Index: 89.6
Adjusted: $142,532
St. Louis
Nominal: $136,120
CoL Index: 95.088
Adjusted: $143,152

Cost-of-living adjustment: salary × (100 / CoL index). Index of 100 = national average.

Which City Is Right for You?

Choose Nixa if…

  • You prefer the Missouri area and lifestyle

Choose St. Louis if…

  • Higher median salary ($136,120/year)
  • Better top-earner potential ($169,948)
  • Larger job market (3,430 employed)
  • Better purchasing power (CoL-adjusted: $143,152)
  • You prefer the Missouri area and lifestyle

Historical Salary Growth Comparison

Based on BLS OEWS metropolitan area data, nurse practitioner salaries in Nixa grew 22.9% from 2024 to 2025, compared to 31.1% growth in St. Louis over the same period.

Nixa, MO

+22.9%

$100,462 (2024) → $123,450 (2025)

St. Louis, MO

+31.1%

$100,340 (2019) → $131,580 (2025)

View Full Salary Data

Frequently Asked Questions

Which city pays nurse practitioners more: Nixa or St. Louis?

St. Louis has a higher median nurse practitioner salary at $136,120/year, compared to Nixa at $127,709/year — a difference of $8,411 (6.59%).

What is the hourly rate difference between Nixa and St. Louis?

Nixa nurse practitioners earn $61.40/hr while St. Louis hygienists earn $65.44/hr (2026 est.).

Should I relocate from Nixa to St. Louis as a nurse practitioner?

Consider more than just salary when comparing Nixa and St. Louis. Factor in cost of living (CoL-adjusted: Nixa = $142,532, St. Louis = $143,152), job availability (6 vs 3,430 employed), commute, and career growth potential.

What do entry-level nurse practitioners earn in Nixa vs St. Louis?

Entry-level (10th percentile) nurse practitioners earn $103,363 in Nixa and $112,078 in St. Louis. The St. Louis area offers higher starting salaries.

Related Comparisons

MG

Written by Maria Gonzalez, MSN, NP-C

Career Analyst

Maria has 10 years of experience in adult healthcare. She works in a community health clinic. Her specialty is chronic disease management.

Clinically reviewed by James Patel, DNP, APRNData verified by Aisha Khan, MSN, FNP-BC

Methodology & Data Source

All salary figures are 2026 projections based on BLS OEWS May 2025 data. A 3.45% CAGR (derived from 6-year national BLS trends) was applied to estimate current compensation. Cost-of-living adjustments use BEA Regional Price Parity data. Actual salaries vary by employer, certifications, and experience.

Data Sources & Methodology

Source: BLS, OEWS , released .

Compiled and verified by Maria Gonzalez, MSN, NP-C, a licensed nurse practitioner with 10+ years of clinical experience. · View source data at BLS.gov