Nurse Practitioner Hourly Pay in St. Louis, MO: $65.44 (2026)
Quick Answer:Hourly pay for a nurse practitioner working in St. Louis, MO runs $65.44 at the median for 2026 — annualizing to $136,120 at a standard 2,080-hour year. Figures projected from BLS OEWS 2025 (SOC 29-1171). Weighted against St. Louis's regional price level (BEA RPP 95.1, 5% below national), each hour of work buys what $68.82 nationally would. A 24-hour part-time schedule grosses $81,672 per year.
Official BLS data · View source
In St. Louis, Missouri, the projected nurse practitioner hourly pay for 2026 is $65.44, slightly below the national median hourly rate of $65.80. This compensation level offers a solid foundation for those considering part-time positions or per diem work. For example, a nurse practitioner working three days a week could potentially earn nearly $102,000 annually, making this career appealing for flexible employment situations typical in environments such as primary care exam rooms, urgent care facilities, and telehealth services. The hourly pay range for nurse practitioners in St. Louis extends from $53.89 for entry-level positions to $81.70 for experienced professionals, reflecting the diverse roles available within the healthcare system. These figures, based on 2025 BLS OEWS data projected to 2026, highlight the potential for rewarding hourly wages across various clinical settings within the region.
Nurse Practitioner Hourly Wage Breakdown
| Percentile | Hourly Rate | Per 8hr Shift |
|---|---|---|
| Entry Level (P10) | $53.89 | $431.10 |
| Lower Range (P25) | $63.39 | $507.15 |
| Median (P50) | $65.44 | $523.54 |
| Upper Range (P75) | $76.84 | $614.74 |
| Top Earners (P90) | $81.70 | $653.64 |
Estimated Annual Income by Work Schedule in St. Louis
Based on $65.44/hr median hourly rate · 2026 est.
At $65.44/hr, a nurse practitioner working full-time (40 hr/wk) in St. Louis, MO can expect to earn approximately $136,120 per year (2026 est.). Part-time hygienists working 24 hours per week would earn around $78,531. With a cost-of-living index of 95.09 (below the national average), these earnings stretch further in St. Louis.
Hourly Rate Calculator
Schedule Comparison in St. Louis
| Schedule | Weekly | Monthly | Annual |
|---|---|---|---|
| Full-Time (40 hrs) | $2,617.70 | $11,343 | $136,120 |
| Part-Time (24 hrs) | $1,570.62 | $6,806 | $81,672 |
| Per Diem (16 hrs) | $1,047.08 | $4,537 | $54,448 |
Compare NP Wages With Similar Roles
| Role | Median Hourly |
|---|---|
| Nurse Practitioner (St. Louis) | $65.44 |
| Registered Nurse (National Avg) | $42.80 |
| Physician Assistant (National Avg) | $63.20 |
| Nurse Anesthetist (National Avg) | $103.40 |
| Nurse Midwife (National Avg) | $63.85 |
Nurse Practitioners in St. Louis, MO earn a median of $136,120 per year (2026 est.), which is 0.54% lower than the national median of $136,864 and 2.10% above the Missouri state average of $133,320.
Nurse Practitioner Hourly Pay vs. Cost of Living
Working 24h/week at $65.44/hr = $81,672/year (purchasing power: $85,891).
Working 40h/week (full-time) = $136,120/year (purchasing power: $143,152).
CoL index: 95.088 (100 = national average). Your dollars stretch further here.
2019 BLS Actual
$48.24/hr
2025 BLS Actual
$63.26/hr
2026 Current Est.
$65.44/hr
2019–2027 Growth
+40.3%
Hourly Rate Trajectory for Nurse Practitioners in St. Louis (2019–2027)
2019–2025: actual BLS OEWS data for this metro area. 2026+: CAGR 3.45% projection.
| Year | Hourly Rate | Status |
|---|---|---|
| 2019 | $48.24/hr | Actual |
| 2020 | $49.43/hr | Actual |
| 2021 | $48.94/hr | Actual |
| 2022 | $51.19/hr | Actual |
| 2023 | $57.19/hr | Actual |
| 2024 | $62.21/hr | Actual |
| 2025 | $63.26/hr | Actual |
| 2026(current) | $65.44/hr | Estimated |
| 2027 | $67.70/hr | Projected |
Based on 7 years of BLS OEWS metropolitan area data, the median hourly rate for nurse practitioners in St. Louis grew 31.1% from $48.24/hr (2019) to $63.26/hr (2025). At a 3.45% projected growth rate, hourly pay is expected to reach $67.70/hr by 2027. Part-time and per-diem nurse practitioners can use this multi-year trend to benchmark future contract negotiations.
Note: Historical values (2019–2025) are actual BLS OEWS figures for the St. Louis metropolitan area, sourced from annual Occupational Employment and Wage Statistics surveys. 2026–2026 figures are current estimates, and 2027 values are projections, calculated using a 3.45% CAGR derived from 7-year BLS historical data. Actual salaries may vary based on employer, experience, certifications, and local market conditions.
Working as an Hourly Nurse Practitioner in St. Louis
The earning prospects for a nurse practitioner in St. Louis can differ significantly based on employment status. Working as a part-time nurse practitioner, for instance, allows for a tailored schedule but generally means less annual income compared to full-time roles. Those opting for per diem or locum positions might find the pay varies substantially, with locum nurse practitioners billing anywhere from $80 to $140 an hour, while psychiatric mental health nurse practitioners engaging in telehealth sometimes command rates between $150 and $200 per hour. Varied employer types present a spectrum of compensation; for example, hospital outpatient clinics and retail clinics might offer lower hourly rates but provide benefits, while independent practices could yield higher pay for those willing to forgo employer-sponsored health insurance. As such, nurse practitioners in St. Louis must weigh the financial trade-offs and consider negotiations strategically to enhance their hourly pay and overall compensation in this evolving field.
More salary data for St. Louis, MO:
Frequently Asked Questions
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Written by Maria Gonzalez, MSN, NP-C
Career Analyst
Maria has 10 years of experience in adult healthcare. She works in a community health clinic. Her specialty is chronic disease management.
Methodology & Data Source
Hourly wage figures on this page are 2026 projections based on the Bureau of Labor Statistics Occupational Employment and Wage Statistics (OEWS) survey, May 2026 release. A 3.45% compound annual growth rate (CAGR), derived from 6-year national BLS wage trends, was applied to estimate current 2026 hourly rates for nurse practitioners in St. Louis. Part-time and full-time income estimates assume consistent weekly hours and do not account for overtime, benefits, or seasonal variation.
Data Sources & Methodology
Source: BLS, OEWS, 7-year dataset (–). Per-city data from annual BLS metropolitan area surveys.
2026 figures are projected from 2025 BLS data using a compound annual growth rate (CAGR) of 3.45%, derived from historical BLS wage trends for nurse practitioners (SOC 29-1171).
Compiled and verified by Maria Gonzalez, MSN, NP-C, a licensed nurse practitioner with 10+ years of clinical experience. · View source data at BLS.gov