Nurse Practitioner Hourly Pay in Cape Girardeau, MO: $64.66 (2026)
Quick Answer:Hourly pay for a nurse practitioner working in Cape Girardeau, MO runs $64.66 at the median for 2026 — annualizing to $134,485 at a standard 2,080-hour year. Figures projected from BLS OEWS 2025 (SOC 29-1171). Weighted against Cape Girardeau's regional price level (BEA RPP 86.1, 14% below national), each hour of work buys what $75.11 nationally would. A 24-hour part-time schedule grosses $80,691 per year.
Official BLS data · View source

In Cape Girardeau, Missouri, the nurse practitioner hourly pay stands at $64.66, which is slightly below the national median hourly rate of $65.80. This rate reflects an encouraging opportunity for part-time or per-diem nurse practitioners who may work in various settings, such as primary care exam rooms, hospital outpatient clinics, or telehealth platforms. For those seeking flexibility, working three days a week at this hourly rate translates to a solid income, while experienced practitioners could earn from $48.41 at the entry level up to $74.11 as the top earners in the region. These figures are derived from the official data based on 2025 BLS OEWS data, projected to 2026, providing a realistic outlook for aspiring nurse practitioners in Cape Girardeau.
Nurse Practitioner Hourly Wage Breakdown
| Percentile | Hourly Rate | Per 8hr Shift |
|---|---|---|
| Entry Level (P10) | $48.41 | $387.32 |
| Lower Range (P25) | $59.43 | $475.46 |
| Median (P50) | $64.66 | $517.25 |
| Upper Range (P75) | $69.48 | $555.82 |
| Top Earners (P90) | $74.11 | $592.89 |
Estimated Annual Income by Work Schedule in Cape Girardeau
Based on $64.66/hr median hourly rate · 2026 est.
At $64.66/hr, a nurse practitioner working full-time (40 hr/wk) in Cape Girardeau, MO can expect to earn approximately $134,485 per year (2026 est.). Part-time hygienists working 24 hours per week would earn around $77,588. With a cost-of-living index of 86.08 (below the national average), these earnings stretch further in Cape Girardeau.
Hourly Rate Calculator
Schedule Comparison in Cape Girardeau
| Schedule | Weekly | Monthly | Annual |
|---|---|---|---|
| Full-Time (40 hrs) | $2,586.25 | $11,207 | $134,485 |
| Part-Time (24 hrs) | $1,551.75 | $6,724 | $80,691 |
| Per Diem (16 hrs) | $1,034.50 | $4,483 | $53,794 |
Compare NP Wages With Similar Roles
| Role | Median Hourly |
|---|---|
| Nurse Practitioner (Cape Girardeau) | $64.66 |
| Registered Nurse (National Avg) | $42.80 |
| Physician Assistant (National Avg) | $63.20 |
| Nurse Anesthetist (National Avg) | $103.40 |
| Nurse Midwife (National Avg) | $63.85 |
Nurse Practitioners in Cape Girardeau, MO earn a median of $134,485 per year (2026 est.), which is 1.74% lower than the national median of $136,864 and 0.90% above the Missouri state average of $133,285.
Nurse Practitioner Hourly Pay vs. Cost of Living
Working 24h/week at $64.66/hr = $80,691/year (purchasing power: $93,742).
Working 40h/week (full-time) = $134,485/year (purchasing power: $156,236).
CoL index: 86.078 (100 = national average). Your dollars stretch further here.
2019 BLS Actual
$51.88/hr
2025 BLS Actual
$62.50/hr
2026 Current Est.
$64.66/hr
2019–2027 Growth
+28.9%
Hourly Rate Trajectory for Nurse Practitioners in Cape Girardeau (2019–2027)
2019–2025: actual BLS OEWS data for this metro area. 2026+: CAGR 3.45% projection.
| Year | Hourly Rate | Status |
|---|---|---|
| 2019 | $51.88/hr | Actual |
| 2020 | $48.69/hr | Actual |
| 2021 | $47.84/hr | Actual |
| 2022 | $57.86/hr | Actual |
| 2023 | $58.06/hr | Actual |
| 2024 | $60.75/hr | Actual |
| 2025 | $62.50/hr | Actual |
| 2026(current) | $64.66/hr | Estimated |
| 2027 | $66.89/hr | Projected |
Based on 7 years of BLS OEWS metropolitan area data, the median hourly rate for nurse practitioners in Cape Girardeau grew 20.5% from $51.88/hr (2019) to $62.50/hr (2025). At a 3.45% projected growth rate, hourly pay is expected to reach $66.89/hr by 2027. Part-time and per-diem nurse practitioners can use this multi-year trend to benchmark future contract negotiations.
Note: Historical values (2019–2025) are actual BLS OEWS figures for the Cape Girardeau metropolitan area, sourced from annual Occupational Employment and Wage Statistics surveys. 2026–2026 figures are current estimates, and 2027 values are projections, calculated using a 3.45% CAGR derived from 7-year BLS historical data. Actual salaries may vary based on employer, experience, certifications, and local market conditions.
Working as an Hourly Nurse Practitioner in Cape Girardeau
Examining nurse practitioner compensation in Cape Girardeau reveals intriguing insights, especially for those considering part-time options or per-diem work. A nurse practitioner working 24 hours per week might take home significantly less annually than a full-time counterpart, leading to potential considerations about job flexibility versus financial stability. For locum tenens positions, nurse practitioners can charge between $80 and $140 per hour, with psychiatric nurse practitioners often earning even more through telehealth services, potentially reaching $150 to $200 per hour when managing remote medication appointments. The complexity of wage variation across different employer types underscores the importance of strategic career choices; urgent care centers, retail clinics, and telehealth platforms may offer different hourly rates. Ultimately, nurse practitioners should weigh the trade-offs between higher pay without benefits versus more stable hourly rates that include insurance. For negotiation, it’s advisable to research local market rates and be prepared to discuss the value of specific skills, particularly in in-demand specialties, in order to secure the best possible compensation.
More salary data for Cape Girardeau, MO:
Frequently Asked Questions
What is the hourly rate for nurse practitioners in Cape Girardeau in 2026?
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Written by Maria Gonzalez, MSN, NP-C
Career Analyst
Maria has 10 years of experience in adult healthcare. She works in a community health clinic. Her specialty is chronic disease management.
Methodology & Data Source
Hourly wage figures on this page are 2026 projections based on the Bureau of Labor Statistics Occupational Employment and Wage Statistics (OEWS) survey, May 2026 release. A 3.45% compound annual growth rate (CAGR), derived from 6-year national BLS wage trends, was applied to estimate current 2026 hourly rates for nurse practitioners in Cape Girardeau. Part-time and full-time income estimates assume consistent weekly hours and do not account for overtime, benefits, or seasonal variation.
Data Sources & Methodology
Source: BLS, OEWS, 6-year dataset (–). Per-city data from annual BLS metropolitan area surveys.
2026 figures are projected from 2025 BLS data using a compound annual growth rate (CAGR) of 3.45%, derived from historical BLS wage trends for nurse practitioners (SOC 29-1171).
Compiled and verified by Maria Gonzalez, MSN, NP-C, a licensed nurse practitioner with 10+ years of clinical experience. · View source data at BLS.gov